Scientists test re-engineered immune cells to fight untreatable MS

NCT ID NCT06451159

Summary

This is an early-phase study testing a new personalized cell therapy called KYV-101 in 10 people with progressive multiple sclerosis (MS) that hasn't improved with standard treatments. Researchers will collect a patient's own immune cells, modify them in a lab to target B cells thought to drive MS, and infuse them back. The main goals are to check if the modified cells reach the brain and spinal cord and to find the safest dose.

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Contacts and locations

Locations

  • University of California, San Francisco, Multiple Sclerosis Center

    San Francisco, California, 94158, United States

Conditions

Explore the condition pages connected to this study.