Modified immune cells target untreatable lupus in groundbreaking trial

NCT ID NCT06585514

First seen Nov 01, 2025 · Last updated Apr 17, 2026 · Updated 24 times

Summary

This early-phase study is testing a new cell therapy for people with severe lupus that hasn't responded to standard treatments. Researchers will give participants a one-time infusion of their own genetically modified immune cells (called CD19 CAR T cells) designed to attack the faulty B cells thought to drive lupus. The main goals are to find a safe dose and see if this approach can effectively control the disease in 18 children and adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing GoBroad Hospital

    RECRUITING

    Beijing, Beijing Municipality, 102206, China

Conditions

Explore the condition pages connected to this study.