New immune therapy targets deadliest brain tumors

NCT ID NCT04214392

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This early-phase trial tests a new type of immune cell therapy (CAR T cells) designed to target and kill glioblastoma, an aggressive brain cancer that has returned or worsened. The therapy uses a special targeting domain (chlorotoxin) to seek out cancer cells. The study involves 19 participants and focuses on finding the safest dose and understanding side effects.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.