Revolutionary Cancer-Fighting cells turned against autoimmune diseases in groundbreaking trial

NCT ID NCT06220201

Summary

This early-stage study is testing whether a modified immune cell therapy called CC-97540 is safe for people with multiple sclerosis or myasthenia gravis. The treatment uses specially engineered T-cells that target CD19, a protein on certain immune cells thought to drive these autoimmune conditions. Researchers will enroll 120 participants across three groups to determine the safest dose and monitor for side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Antwerp University Hospital

    RECRUITING

    Edegem, Antwerpen, 2650, Belgium

    Contact Phone: •••-•••-••••

  • Barts Health NHS Trust

    RECRUITING

    London, E1 1RD, United Kingdom

    Contact Phone: •••-•••-••••

  • Cleveland Clinic Mellen Center

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-••••

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

    Contact Phone: •••-•••-••••

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-••••

  • Hopital Claude Huriez - CHU de Lille

    RECRUITING

    Lille, Nord, 59000, France

    Contact Phone: •••-•••-••••

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, Catalunya [Cataluña], 08036, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, Barcelona [Barcelona], 08035, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitari i Politecnic La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, Madrid, Comunidad de, 28034, Spain

    Contact Phone: •••-•••-••••

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-••••

  • Klinikum der Universität München Großhadern

    RECRUITING

    München, 81337, Germany

    Contact Phone: •••-•••-••••

  • Local Institution - 0005

    COMPLETED

    Boston, Massachusetts, 02114, United States

  • Local Institution - 0016

    NOT_YET_RECRUITING

    Barcelona, Barcelona [Barcelona], 08035, Spain

    Contact

  • Local Institution - 0033

    COMPLETED

    Düsseldorf, 40225, Germany

  • Local Institution - 0039

    WITHDRAWN

    New Orleans, Louisiana, 70121, United States

  • Manchester Royal Infirmary

    RECRUITING

    Manchester, Lancashire, M20 2RZ, United Kingdom

    Contact Phone: •••-•••-••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-••••

  • Neurological Institute of New York

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-••••

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-••••

  • Pitie Salpetriere University Hospital

    RECRUITING

    Paris, Ville de Paris, 75013, France

    Contact Phone: •••-•••-••••

  • Salford Royal Hospital

    RECRUITING

    Salford, Manchester, M6 8HD, United Kingdom

    Contact Phone: •••-•••-••••

  • Swedish Medical Center

    RECRUITING

    Seattle, Washington, 98122, United States

    Contact Phone: •••-•••-••••

  • UZ Gent

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

    Contact Phone: •••-•••-••••

  • Universitaetsklinikum Erlangen

    RECRUITING

    Erlangen, 91054, Germany

    Contact Phone: •••-•••-••••

  • Universitaetsklinikum Essen

    RECRUITING

    Essen, North Rhine-Westphalia, 45147, Germany

    Contact Phone: •••-•••-••••

  • Universitaetsklinikum Magdeburg

    RECRUITING

    Magdeburg, Saxony-Anhalt, 39120, Germany

    Contact Phone: •••-•••-••••

  • University College London Hospital

    RECRUITING

    London, London, City of, NW1 2PG, United Kingdom

    Contact Phone: •••-•••-••••

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-••••

  • University of California, Irvine

    RECRUITING

    Irvine, California, 92697, United States

    Contact Phone: •••-•••-••••

  • University of Cincinnati Medical Center

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-••••

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-••••

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-••••

  • Yale-New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.