Engineered immune cells take on Hard-to-Treat lung cancer

NCT ID NCT07116057

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This early-stage trial tests a new treatment for people with a specific type of lung cancer that has spread or come back. The therapy uses the patient's own immune cells, modified to target a protein called folate receptor-alpha (FRa) on cancer cells. Ten participants will receive a single dose of these cells directly into the chest cavity after chemotherapy. The main goal is to check safety and see if the treatment is feasible.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.