New combo therapy aims to boost leukemia fight without harming transplant

NCT ID NCT05507827

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This early-phase trial tests whether giving specially engineered donor immune cells (CAR T cells) after a stem cell transplant is safe for adults with a high-risk type of B-cell leukemia. The goal is to strengthen the body's ability to fight remaining cancer cells without causing severe graft-versus-host disease. About 22 participants will receive the treatment and be monitored for side effects and leukemia relapse.

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Contacts and locations

Locations

  • Stanford Cancer Center

    Palo Alto, California, 94305, United States

Conditions

Explore the condition pages connected to this study.