Reprogrammed immune cells target Tough-to-Treat lymphoma in groundbreaking trial

NCT ID NCT01840566

Summary

This early-stage trial is testing the safety of a two-part treatment for aggressive B-cell non-Hodgkin lymphoma that has returned or not responded to other therapies. First, patients receive high-dose chemotherapy and a transplant of their own blood stem cells. Then, they receive an infusion of their own immune cells (T-cells) that have been specially modified in a lab to find and attack their cancer cells. The main goal is to find the safest dose of these modified cells and understand their side effects.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (Limited protocol activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (Limited protocol activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited protocol activites)

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

  • Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

Conditions

Explore the condition pages connected to this study.