Early-Stage trial tests re-engineered immune cells against tough prostate cancers

NCT ID NCT02744287

Summary

This early-stage study tested whether a patient's own immune cells could be modified in a lab to recognize and attack advanced prostate cancer. The treatment, called BPX-601, involved collecting a patient's T-cells, engineering them to target a specific marker on cancer cells, and then infusing them back into the patient. The main goals were to check if this approach was safe and to find the right dose, but the study was stopped before moving to the next phase.

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Contacts and locations

Locations

  • Baylor Sammons Cancer Center

    Dallas, Texas, 75246, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Emory Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • John Theurer Cancer Center, Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Chicago Medicine

    Chicago, Illinois, 60637, United States

  • University of Nebraska

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.