Personalized immune cell therapy tested as potential lifeline for Tough-to-Treat adult leukemia
NCT ID NCT04404660
Summary
This study is testing a personalized cell therapy called AUTO1 for adults with a type of blood cancer (B-cell ALL) that has come back or hasn't responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab to better target cancer cells, and then infuse them back into the patient. The main goals are to see if the treatment is safe and if it can help put the cancer into remission.
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Contacts and locations
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Locations
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Baylor Scott & White Research Institute
Dallas, Texas, 75246, United States
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Cambridge University Hospitals NHS Foundation Trust
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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City of Hope National Medical Center
Duarte, California, 93534, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Colorado Blood Cancer Institute (CBCI)
Denver, Colorado, 80218, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, Tyne and Wear, NE7 7DN, United Kingdom
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Fundacio' Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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H Lee Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Hospital Universitario La Fé
Valencia, 46026, Spain
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Hospital Universitario Virgen del Rocío
Seville, 41013, Spain
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King's College Hospital
London, Greater London, SE5 9RS, United Kingdom
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Manchester Royal Infirmary Hospital
Manchester, Greater Manchester, M13 9WL, United Kingdom
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Queen Elizabeth University Hospital
Glasgow, Scotland, G514TF, United Kingdom
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TTI-Methodist (Texas Transplant Institute) (SCRI)
San Antonio, Texas, 78229, United States
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The Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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TriStar Centennial Medical Center (SCRI)
Nashville, Tennessee, 37203, United States
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University College London Hospitals NHS Foundation Trust
London, Greater London, NW1 2PG, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust
Birmingham, West Midlands, B15 2GW, United Kingdom
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University Hospitals Bristol and Weston NHS Foundation Trust (UHBW)
Bristol, BS2 8ED, United Kingdom
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University of California Davis (UC Davis)
Sacramento, California, 95817, United States
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University of California San Diego Health (UCSD)
La Jolla, California, 92093, United States
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University of California San Francisco (UCSF)
San Francisco, California, 94143, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Kansas
Kansas City, Kansas, 66160, United States
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University of Maryland Medical Center
Baltimore, Maryland, 21201, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Nebraska
Omaha, Nebraska, 68105, United States
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University of Rochester
Rochester, New York, 14642, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Winship Cancer Institute of Emory University
Atlanta, Georgia, 30322, United States
Conditions
Explore the condition pages connected to this study.