First-in-Lupus trial tests 'Living Drug' to reset the immune system

NCT ID NCT06333483

Recruiting now Disease control Sponsor: Autolus Limited Source: ClinicalTrials.gov ↗

Summary

This is an early-stage safety study testing a new type of treatment called CAR-T cell therapy for people with severe lupus that hasn't responded to other treatments. Doctors will collect a patient's own immune cells, modify them in a lab to target lupus-causing cells, and infuse them back. The main goal is to see if this one-time treatment is safe and tolerable, while also checking for early signs that it might help control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Addenbrookes Hospital
RECRUITING

Cambridge, CB2 0QQ, United Kingdom

Contact Email: •••••@•••••
Great Ormond Street Hospital
RECRUITING

London, WC1N 3JH, United Kingdom

Contact Email: •••••@•••••
Hospital Universitari Vall Hebrón
RECRUITING

Barcelona, 08035, Spain

Contact Email: •••••@•••••
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, 106046026, Spain

Contact Email: •••••@•••••
Manchester Royal Infirmary, Manchester University NHS Foundation Trust,
RECRUITING

Manchester, M13 9WL, United Kingdom

Contact Email: •••••@•••••
University College London Hospitals NHS Foundation Trust
RECRUITING

London, NW1 2PG, United Kingdom

Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

SYSTEMIC LUPUS ERYTHEMATOSUS