Scientists test 'Living Drug' to reset immune system in severe autoimmune patients

NCT ID NCT07038447

Summary

This is an early-stage study testing a new personalized cell therapy called KITE-363 for people with severe autoimmune diseases that haven't improved with standard treatments. The therapy involves modifying a patient's own immune cells to target and remove harmful B cells, which are thought to drive these diseases. The main goals are to find a safe dose and see if the treatment shows early signs of helping conditions like lupus, lupus nephritis, scleroderma, and inflammatory muscle disease.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Concord Repatriation General Hospital

    Syndey, New South Wales, 2139, Australia

  • Jewish General Hospital

    Montreal, H3T1E2, Canada

  • St Vincent's Hospital

    Fitzroy, Victoria, 3065, Australia

  • Stanford University

    Stanford, California, 94305, United States

Conditions

Explore the condition pages connected to this study.