Experimental CAR T-Cell therapy for T-Cell lymphoma halted early

NCT ID NCT03590574

First seen Mar 25, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This study tested a new treatment called AUTO4 for people with a rare and aggressive type of T-cell lymphoma that had come back or not responded to other treatments. The treatment used the patient's own immune cells, modified to target and kill cancer cells. The study was stopped early, and the results help researchers understand the safety and activity of this approach.

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Contacts and locations

Locations

  • Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust

    Newcastle upon Tyne, United Kingdom

  • Manchester Royal Infirmary Hospital

    Manchester, United Kingdom

  • Queen Elizabeth University Hospital

    Glasgow, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    London, United Kingdom

  • Vall d'Hebron Institute of Oncology

    Barcelona, Spain

Conditions

Explore the condition pages connected to this study.