Experimental CAR-T therapy targets tough lymphoma in small safety trial

NCT ID NCT07447726

First seen Mar 12, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This early-phase study tests a new type of CAR-T cell therapy (CD19X) in 3 people with relapsed or refractory large B-cell lymphoma, a blood cancer that has not responded to standard treatments. The main goal is to check safety, looking for side effects like cytokine release syndrome and nerve problems. Researchers will also measure how well the treatment shrinks tumors and how long the CAR-T cells stay in the body.

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