New combo therapy aims to outsmart tough hodgkin lymphoma

NCT ID NCT04134325

First seen Apr 18, 2026 · Last updated May 09, 2026 · Updated 1 time

Summary

This small pilot study tests whether giving a PD-1 inhibitor after CAR-T cell therapy can improve outcomes for people with Hodgkin lymphoma that has come back or not responded to treatment. Ten adults who have already tried at least three prior therapies will receive standard anti-PD-1 treatment after their CAR-T cells stop working. The goal is to see if this sequence can trigger a stronger immune response and shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Lineberger Comprehensive Cancer Center at University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.