First human test of experimental cancer drug shows early promise
NCT ID NCT04417465
Summary
This first-in-human study tested the safety of an experimental cancer drug called ABBV-CLS-579, both alone and combined with other cancer treatments. The trial enrolled 101 adults with advanced solid tumors who had exhausted standard treatment options. Researchers aimed to find safe dosage levels and gather early information about how the drug behaves in the body and whether it shows any effectiveness against cancer.
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Contacts and locations
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Locations
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Carolina BioOncology Institute
Huntersville, North Carolina, 28078, United States
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Fort Wayne Medical Oncology and Hematology
Fort Wayne, Indiana, 46804, United States
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Highlands Oncology Group Springdale
Springdale, Arkansas, 72762, United States
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Hopital Saint-Andre
Bordeaux, 33000, France
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Hospital Universitario HM Sanchinarro
Madrid, 28050, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Institut Gustave Roussy
Villejuif, 94805, France
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa-Shi, Chiba, 277-8577, Japan
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National Taiwan University Hospital
Taipei, 100, Taiwan
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Seoul National University Hospital
Seoul, 03080, South Korea
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The Chaim Sheba Medical Center
Ramat Gan, 5262100, Israel
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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Wakayama Medical University Hospital
Wakayama, Wakayama, 641-8510, Japan
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Yale University
New Haven, Connecticut, 06519, United States
Conditions
Explore the condition pages connected to this study.