New drug duo aims to reboot immune system against tough cancers

NCT ID NCT03156114

Summary

This early-stage study tested a combination of two immunotherapy drugs (BI 754111 and BI 754091) in adults with advanced solid tumors, including non-small cell lung cancer. The first goal was to find the safest highest dose. The second goal was to see if this combination could shrink tumors in patients whose cancer had returned after previous immunotherapy. Treatment was given by IV every three weeks for up to one year.

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Contacts and locations

Locations

  • BioVirtus Research Site Sp. z o.o.

    Józefów, 05-410, Poland

  • Cross Cancer Institute (University of Alberta)

    Edmonton, Alberta, T6G 1Z2, Canada

  • Florida Cancer Specialists

    Sarasota, Florida, 34232, United States

  • Froedtert and The Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Politècnic La Fe

    Valencia, 46026, Spain

  • Hospital Universitari Dexeus

    Barcelona, 08028, Spain

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • John Theurer Cancer Center

    Hackensack, New Jersey, 07601, United States

  • Oncology Center-Maria Sklodowska-Curie Institute

    Warsaw, 02-781, Poland

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 1Z9, Canada

  • Sarah Cannon Research Institute

    London, W1G 6AD, United Kingdom

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • University of Miami

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.