New drug duo tested to fight tough cancers

NCT ID NCT06130254

Summary

This early-phase trial is testing the safety and best dose of a combination of two targeted drugs, adagrasib and olaparib, for people with advanced solid tumors that have a specific genetic change called a KRAS G12C mutation. It will enroll about 52 adults with cancers like pancreatic, breast, gynecological, or certain lung cancers that have progressed after standard treatments. The main goal is to see if the drugs can be given together safely and to look for early signs that they might help control the cancer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.