New drug duo tested in fight against Tough-to-Treat cancers

NCT ID NCT06302621

Summary

This early-stage study is testing the safety and initial effectiveness of combining two targeted cancer drugs, pemigatinib and afatinib, in people with advanced solid tumors that have specific genetic changes and have stopped responding to standard treatments. The main goals are to find the highest dose that can be given safely and to see if the combination can shrink tumors, particularly in a type of bile duct cancer. About 70 participants with advanced cancer will receive the drug combination for as long as it helps them and they can tolerate the side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.