Scientists test new Two-Drug attack on tough cancers

NCT ID NCT03905148

Summary

This early-stage study tested the safety and initial effects of combining two oral drugs, BGB-283 and PD-0325901, in adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and see if the drug combination could shrink tumors. The study involved 91 participants with various cancers, including lung, colorectal, ovarian, and melanoma.

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Contacts and locations

Locations

  • Blacktown Cancer and Haematology Centre

    Blacktown, New South Wales, 2148, Australia

  • Linear Clinical Research

    Nedlands, Western Australia, 6009, Australia

  • MD Anderson

    Houston, Texas, 77030, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • The Prince of Wales Private Hospital - Specialist Medical Randwick

    Randwick, New South Wales, 2031, Australia

  • University of California Los Angeles

    Santa Monica, California, 90404, United States

Conditions

Explore the condition pages connected to this study.