Scientists test new Cancer-Fighting duo in early safety trial

NCT ID NCT03239145

Summary

This early-stage study tested the safety of combining two drugs, pembrolizumab and AMG386, in 62 patients with advanced solid tumors like melanoma, ovarian, kidney, or colorectal cancer. The goal was to see if the combination was safe and to find the right dose, as lab research suggested the drugs might work better together. The study also looked for early signs that the treatment could help control the cancer.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.