Can a drug block inflammation and lower lung cancer risk in Ex-Smokers?

NCT ID NCT06038526

First seen Jan 07, 2026 · Last updated Apr 28, 2026 · Updated 13 times

Summary

This study looks at how canakinumab, a drug that reduces inflammation, affects cells in the mouth, nose, and blood of former smokers who are at high risk for lung cancer. The goal is to see if blocking a specific inflammatory protein can slow or prevent cancer growth. About 41 participants will provide samples before and after treatment to measure changes in key markers.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.