Can a drug calm the bone marrow storm in myelofibrosis?

NCT ID NCT05467800

First seen Nov 18, 2025 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study tests a drug called canakinumab in people with myelofibrosis, a serious bone marrow disorder. The goal is to see if it can improve symptoms, anemia, or reduce an enlarged spleen. About 14 adults will receive injections every 3 weeks for 8 cycles, and researchers will check for side effects and signs of improvement.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Atrium Health Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute

    NOT_YET_RECRUITING

    Los Angeles, California, 90048, United States

    Contact

  • Cleveland Clinic Foundation

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

  • Mayo Clinic Arizona

    WITHDRAWN

    Phoenix, Arizona, 85259, United States

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

  • Ruttenberg Treatment Center

    RECRUITING

    New York, New York, 10029, United States

  • The University of Kansas Cancer Center-Westwood

    RECRUITING

    Westwood, Kansas, 66205, United States

    Contact

  • Wake Forest Baptist Health Comprehensive Cancer Center

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact

Conditions

Explore the condition pages connected to this study.