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Brain zaps may reawaken Stroke-Damaged motor pathways

NCT ID NCT07787793

Knowledge-focused Sponsor: Ancor Rebassa Cabrera Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether one session of high-frequency repetitive transcranial magnetic stimulation (rTMS) can increase brain activity in the motor cortex of stroke patients with severe arm weakness. Participants, who have had a stroke more than six months ago and cannot voluntarily move their fingers, will receive either real or sham rTMS. Researchers will map the brain's motor responses before and immediately after the session to see if the stimulation expands the area of detectable activity. The goal is to explore whether rTMS could help restore voluntary movement in severely impaired limbs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-frequency repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could point toward a way to jump-start brain recovery in stroke patients with severe arm weakness, potentially improving rehabilitation outcomes.
What could go wrong
This is a small, early-stage trial testing only a single session, so any effects may be temporary or not translate to real-world improvement. There is also a small risk of seizures or discomfort from the stimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * First-ever stroke confirmed by MRI or CT scan. * Inability to voluntarily activate the hand musculature: manual muscle testing score of 1 or less in finger extension. * Time since stroke onset greater than 6 months. Exclusion Criteria: * History of craniotomy or metallic implants in the skull. * Diagnosis of uncontrolled epilepsy. * Diagnosis of other neurological diseases (dementia, Parkinson's disease, neuropathies, multiple sclerosis, or similar conditions). * Low level of consciousness or significant cognitive impairment that prevents informed consent or study collaboration. * Diagnosis of rheumatic disease or presence of hand deformities. * Pregnancy.

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Conditions

The condition(s) this trial relates to.

Diaschisis Paresis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke Upper limb paresis

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Sant Joan de Déu Palma

    RECRUITING

    Palma, Balearic Islands, 07007, Spain

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