Could your own blood heal your jaw after a tooth extraction?
NCT ID NCT07585123
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a substance made from a patient's own blood, called platelet-rich fibrin (L-PRF), can prevent a serious condition called jawbone death after tooth extraction. The trial will include 40 people at high risk due to past radiation or certain medications. Half will get L-PRF in the extraction socket, and half will get standard care, with healing checked over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Platelet-rich fibrin (L-PRF) made from the patient's own blood
- What this could lead to
- If it works, this could point toward a simple, low-cost way to prevent severe jawbone damage in people who have had radiation or take certain bone medications.
- What could go wrong
- This is a very small, early feasibility trial with only 40 people. It may not show a clear benefit, and the results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Morriston Hospital
Swansea, SA6 6NL, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.