Leukemia drug holiday: can patients stop imatinib without relapse?

NCT ID NCT01343173

First seen May 21, 2026 · Last updated Jun 05, 2026 · Updated 3 times

Summary

This study looked at whether people with chronic myeloid leukemia (CML) who had been in complete remission for at least two years could stop taking imatinib without the cancer coming back. Researchers followed 220 adults to see how many stayed in remission and what factors predicted a relapse. The goal was to identify who might safely stop treatment and who needs to continue or switch therapies.

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Contacts and locations

Locations

  • C.H.U. Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • CH Annecy

    Annecy, France

  • CH Bretagne Atlantique

    Vannes, France

  • CH Régional de l'ILE DE LA REUNION/ Groupe Hospitalier Sud

    Saint-Pierre, France

  • CH Sud Francilien

    Corbeil-Essonnes, France

  • CH Valence

    Valence, France

  • CH Yves Le Foll

    Saint-Brieuc, France

  • CHR La Réunion

    Saint-Denis, 97405, France

  • CHU Bensançon

    Besançon, France

  • CHU Caen

    Caen, France

  • CHU Dupuytren

    Limoges, France

  • CHU Grenoble

    Grenoble, 38043, France

  • CHU Hôtel-Dieu

    Nantes, 44035, France

  • CHU de Nice - Hôpital Archet 1

    Nice, 06202, France

  • Centre Henri Becquerel

    Rouen, France

  • Centre Hospitalier - La Roche sur Yon

    La Roche-sur-Yon, 85025, France

  • Centre Hospitalier de Nevers

    Nevers, 58033, France

  • Centre Hospitalier de Versailles - Hôpital André Mignot

    Versailles, 78157, France

  • Hôpital Edouard Herriot

    Lyon, 69374, France

  • Hôpital Henri-Mondor

    Créteil, 94000, France

  • Hôpital Morvan

    Brest, 29285, France

  • Hôpital Necker-Enfants Malades

    Paris, 75743, France

  • Hôpital Pontchaillou

    Rennes, 35033, France

  • Hôpital Purpan

    Toulouse, 31059, France

  • Hôpital Saint Louis

    Paris, 75475, France

  • Hôpitaux civils de Colmar

    Colmar, 68000, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Paoli Calmette

    Marseille, 13273, France

  • Lille University hospital - Hôpital Claude Huriez

    Lille, 59037, France

  • University Hospital Angers

    Angers, 49033, France

  • University Hospital Bordeaux, Hôpital du Haut Lévêque

    Pessac, 33604, France

  • University Hospital Poitiers - Hôpital Jean Bernard

    Poitiers, 86021, France

Conditions

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