Can a single X-Ray predict lung biopsy safety and speed up discharge?
NCT ID NCT06563167
First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
This study tests whether a chest X-ray taken 4 hours after a lung biopsy can predict if a patient will develop a serious complication called pneumothorax (collapsed lung) later. Researchers will compare X-rays taken at different times to see if a clear X-ray at 4 hours means the patient is safe to go home the same day. The study involves 330 patients undergoing image-guided lung biopsies in Hong Kong.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Chest X-ray (CXR) at multiple time points after lung biopsy
- What this could lead to
- If a clear X-ray at 4 hours reliably rules out later complications, many patients could safely go home the same day after a lung biopsy.
- What could go wrong
- This is a single-center study, and the X-ray's accuracy may vary in broader populations. A negative early X-ray does not guarantee no delayed complications.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 330 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who will require image-guided TTLB
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients whose image-guided TTLB, including ultrasound or CT-guided, is arranged for diagnostic purposes * Patients who are able to sign written informed consent to participate in the study Exclusion Criteria: * Patients with resolution of lung lesion prior to the scheduled image-guided TTLB * Patients have active exacerbation of underlying diseases causing unstable respiratory conditions (e.g. exacerbation of COPD, pneumonia) which would lower the threshold for invasive interventions for iatrogenic pneumothorax * Patients with psychiatric disease or cognitive impairment that may limit their ability to understand or give consent to the study * Patients who decline to join the study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chinese University of Hong Kong
Hong Kong, Hong Kong
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