Two-drug combo aims to shrink esophageal tumors before surgery

NCT ID NCT07191977

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times

Summary

This phase 2 trial tests whether giving camrelizumab (an immunotherapy) and palbociclib (a targeted therapy) before surgery can safely shrink tumors in people with esophageal squamous cell carcinoma that can be removed. About 41 adults aged 18-75 with resectable cancer will receive the drug combination, then have surgery. The main goal is to see how many patients have a major reduction in tumor cells after treatment.

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