New shot could shrink enlarged livers and ease pain

NCT ID NCT05281328

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called CAM2029 (octreotide) given as a weekly or every-other-week shot to people with symptomatic polycystic liver disease. The goal is to see if it can shrink the liver and reduce symptoms like belly pain, bloating, and nausea. About 71 adults with an enlarged liver will be randomly assigned to receive the drug or a placebo for 53 weeks, with an option to continue on the drug for another 120 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant polycystic kidney disease autosomal dominant polycystic liver disease Polycystic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bon Secours Richmond Community Hospital

    Richmond, Virginia, 23602, United States

  • Hannover Medical School

    Hanover, 30625, Germany

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • Radboud UMC, Department of Gastroenterology and Hepatology

    Nijmegen, 6525 GA, Netherlands

  • The New York Presbyterian Hospital

    New York, New York, 10065, United States

  • Universitaetsklinikum Müenster

    Münster, 48149, Germany

  • University Hospitals KU Leuven

    Leuven, B-3000, Belgium

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75380-8887, United States

  • Universitätsklinikum Leipzig

    Leipzig, 04103, Germany