Calquence capsules pass Real-World safety check in CLL patients

NCT ID NCT05665374

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at the safety of Calquence (acalabrutinib) capsules in 67 people with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma. Researchers tracked side effects like infections and bone marrow problems during everyday use. The goal was to understand how safe the drug is outside of controlled clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Calquence (acalabrutinib) capsules 100 mg

What this could lead to

If successful, this study could confirm that Calquence is safe and manageable for people with untreated CLL in everyday medical practice.

What could go wrong

This is a small, completed safety study, not a large trial testing how well the drug works. Side effects like infections or bone marrow problems may still occur.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic lymphocytic leukemia/small lymphocytic lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Aichi, Japan

  • Research Site

    Chiba, Japan

  • Research Site

    Fukuoka, Japan

  • Research Site

    Hyōgo, Japan

  • Research Site

    Kanagawa, Japan

  • Research Site

    Kyoto, Japan

  • Research Site

    Miyazaki, Japan

  • Research Site

    Nagano, Japan

  • Research Site

    Nara, Japan

  • Research Site

    Okayama, Japan

  • Research Site

    Osaka, Japan

  • Research Site

    Saitama, Japan

  • Research Site

    Shizuoka, Japan

  • Research Site

    Tokyo, Japan

  • Research Site

    Yamanashi, Japan