New global registry aims to unlock secrets of rare heart rhythm disorder

NCT ID NCT06508164

Recruiting now Knowledge-focused Sponsor: Population Health Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This study is creating a worldwide registry for people with Calcium Release Deficiency Syndrome (CRDS), a rare genetic heart condition that can cause dangerous heart rhythms. Researchers will collect health information from 500 participants to better understand the condition's symptoms, risks, and best treatments. The goal is to improve care for people with CRDS by learning from real-world data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this registry could help doctors identify who is at highest risk of dangerous heart rhythms and guide better treatment decisions for people with CRDS.
What could go wrong: This is an observational registry, not a treatment trial, so it won't directly test a new therapy. The condition is newly discovered, so knowledge is still very limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CALCIUM RELEASE DEFICIENCY SYNDROME

Contacts and locations

Locations

Aarhus University Hospital
RECRUITING

Aarhus, DK-8200 N, Denmark
Antwerp University Hospital
RECRUITING

Edegem, Antwerp, 2650, Belgium
CHU de Bordeaux
RECRUITING

Bordeaux, New Aquitaine, 33404, France
Children's & Women's Health Centre of British Columbia
RECRUITING

Vancouver, British Columbia, V6H 3N1, Canada
City St George's, University of London
RECRUITING

London, EC1V 0HB, United Kingdom
Duke University
RECRUITING

Durham, North Carolina, 27710, United States
Garvan Institute of Medical Research
RECRUITING

Darlinghurst, New South Wales, 2010, Australia
Hamilton General Hospital
RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
Inova Health Care Services
RECRUITING

Fairfax, Virginia, 22031, United States
Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval
RECRUITING

Québec, Quebec, Canada
London Health Sciences Centre - University Hospital
RECRUITING

London, Ontario, N6A 5A5, Canada
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Montréal Heart Institute
RECRUITING

Montreal, Quebec, H1T 1C8, Canada
Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada
Oxford University Hospitals
RECRUITING

Oxford, Oxfordshire, 0X3 9DU, United Kingdom
Shaare Zedek Medical Center
RECRUITING

Jerusalem, 9103102, Israel
The University of British Columbia
RECRUITING

Vancouver, British Columbia, V6T 1Z3, Canada
Universitair Ziekenhuis Brussel
RECRUITING

Brussels, 1090, Belgium
University of Calgary
RECRUITING

Calgary, Alberta, T2N 1N4, Canada
University of California
RECRUITING

San Francisco, California, 94143, United States