New combo therapy shows promise for rare gut tumors

NCT ID NCT05249114

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new two-drug combination for people with advanced neuroendocrine tumors (NETs) that have stopped responding to standard treatments. The drugs are cabozantinib (a targeted therapy pill) and Lu-177 DOTATATE (a radioactive treatment that seeks out tumor cells). The main goal is to find the safest dose of cabozantinib when given with the standard dose of Lu-177 DOTATATE. Only 6 participants were enrolled, and the study is no longer recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Providence Portland Cancer Institute - Franz Clinic

    Portland, Oregon, 97213, United States