Triple-Drug cocktail targets rare kidney cancers

NCT ID NCT04413123

First seen Jan 21, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This study tests whether a combination of three drugs (cabozantinib, nivolumab, and ipilimumab) can safely slow the growth of advanced or spreading kidney cancer in people with rare types of the disease. About 60 adults with non-clear cell kidney cancer that cannot be surgically removed or has spread will receive the treatment. The goal is to see how many patients' tumors shrink or disappear, and how long that effect lasts.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Brigham & Woman's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • UT Southwestern Medical

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.