Triple-Drug cocktail shows promise in early prostate cancer trial

NCT ID NCT04477512

First seen Nov 12, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This early-phase study tested a combination of three drugs (cabozantinib, abiraterone, and nivolumab) alongside standard hormone therapy in 18 men with metastatic prostate cancer that still responds to hormone treatment. The main goal was to find a safe dose and check for side effects. Researchers also looked at how well the treatment controlled the cancer, such as lowering PSA levels.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.