Kidney-Friendly? early study checks hepatitis d drug in patients with impaired kidneys
NCT ID NCT05760300
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study looked at how the drug bulevirtide behaves in people with chronic hepatitis D who also have normal or impaired kidney function. Researchers measured drug levels in the blood, its effect on bile acids, and overall safety. The study enrolled 41 adults and gave them multiple doses of bulevirtide by injection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bulevirtide (also known as Hepcludex or Myrcludex B)
What this could lead to
If successful, this study could help doctors understand how to safely use bulevirtide in hepatitis D patients with kidney issues.
What could go wrong
This is a very early (Phase 1) study with only 41 people. It focuses on drug levels and safety, not on curing hepatitis D. Results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Pharma CR, LLC
Miami, Florida, 33147, United States
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Clinical Pharmacology of Miami, LLC
Miami, Florida, 33014, United States
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Floridian Clinical Research, LLC
Miami Lakes, Florida, 33016, United States
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Genesis Clinical Research, LLC
Tampa, Florida, 33603, United States
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Global Clinical Professionals Research
St. Petersburg, Florida, 33705, United States
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Massachusetts General Hospital - Renal Associates Clinic
Boston, Massachusetts, 02114, United States
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Nucleus Network
Saint Paul, Minnesota, 55114, United States
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Panax Clinical Research
Miami Lakes, Florida, 33014, United States
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Velocity Clinical Research, New Smyrna Beach
Edgewater, Florida, 32132, United States