New cancer drugs may harm hearts – study aims to find Who's at risk

NCT ID NCT07174141

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 100 people taking newer BTK inhibitor drugs (acalabrutinib or zanubrutinib) for blood cancers like leukemia or lymphoma. Researchers want to see how often these drugs cause high blood pressure or heart rhythm problems, and find early warning signs. Participants will have eye exams and blood tests over one year to track these risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acalabrutinib, zanubrutinib

What this could lead to

If successful, this could help doctors identify which patients are most at risk for heart problems from these newer cancer drugs, leading to better monitoring and care.

What could go wrong

This is a small, single-center observational study, not a treatment trial. It may not find clear risk factors, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia mantle cell lymphoma non-Hodgkin lymphoma Waldenstrom macroglobulinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Dijon Bourgogne

    RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••