Experimental drug targets fatal brain virus in small trial

NCT ID NCT07511049

First seen Apr 10, 2026 · Last updated Apr 29, 2026 · Updated 2 times

Summary

This study tests whether an antiviral drug called brincidofovir is safe for people with progressive multifocal leukoencephalopathy (PML), a rare and often deadly brain infection caused by the JC virus. About 24 adults with PML will receive the drug through an IV twice a week for up to 12 weeks. Researchers will monitor side effects and check if the drug reduces virus levels in the spinal fluid.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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