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Real-World study checks Brigatinib's performance in ALK-Positive lung cancer

NCT ID NCT05735327

Ongoing Knowledge-focused Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 50 adults with ALK-positive non-small cell lung cancer who are taking brigatinib as their first treatment. Researchers want to see how long the cancer stays under control and how many patients respond to the drug in everyday hospital settings. No new treatment is given—just data collection during regular visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
brigatinib
What this could lead to
If successful, this study could confirm that brigatinib is effective in everyday clinical practice for ALK-positive lung cancer, supporting its continued use.
What could go wrong
This is an observational study, not a controlled trial, so results may be less reliable. It is small (50 participants) and only tracks outcomes, not testing a new approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER (NSCLC)

Contacts and locations

Locations

  • Centrum Onkologii im.Prof. F. Lukaszczyka w Bydgoszczy

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland

  • Centrum Pulmonologii i Torakochirurgii w Bystrej

    Bystra, Slskie, 43-360, Poland

  • Dolnoslskie Centrum Onkologii, Pulmonologii i Hematologii

    Wroclaw, Dolnoslskie, 53-413, Poland

  • Instytut Gruzlicy i Chorob Pluc

    Warsaw, Masovian Voivodeship, 01-138, Poland

  • Krakowski Szpital Specjalistyczny im. Jana Pawla II w Krakowie

    Krakow, Lesser Poland Voivodeship, 31-202, Poland

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie, Panstwowy Instytut Badawczy

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie- Panstwowy Instytut Badawczy Oddzial w Krakowie

    Krakow, Lesser Poland Voivodeship, 31-115, Poland

  • Podkarpackie Centrum Chorob Pluc

    Rzeszów, Podkarpackie Voivodeship, 35-241, Poland

  • SPZOZ Uniwersytecki Szpital Kliniczny nr 2 im. Wojskowej Akademii Medycznej Uniwersytetu Medycznego w Lodzi Centralny Szpital Weteranow

    Lodz, Łódź Voivodeship, 90-549, Poland

  • Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie

    Lublin, Lublin Voivodeship, 20-954, Poland

  • Szpital Kliniczny im. Heliodora Swiecickiego UM wPoznaniu.

    Poznan, Greater Poland Voivodeship, 60-355, Poland

  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu

    Poznan, Greater Poland Voivodeship, 60-569, Poland

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