New drug cocktail could give stroke patients a second chance hours after symptoms start

NCT ID NCT07389460

First seen Feb 05, 2026 · Last updated May 01, 2026 · Updated 11 times

Summary

This study tests whether giving a clot-busting drug (rhPro-UK) before a procedure to remove a large blood clot from the brain can help people who had a stroke 4.5 to 24 hours earlier. About 820 adults with severe stroke symptoms will receive either the drug or a placebo, followed by the standard clot-removal procedure. The goal is to see if the drug improves blood flow and leads to better recovery at 90 days, while also checking for any increased risk of bleeding in the brain.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Provincial People's Hospital

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Loudi Central Hospital

    Loudi, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qinghai Provincial People's Hospital

    Xining, Qinghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanxi Cardiovascular Hospital

    Taiyuan, Shanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Shihezi University

    Shihezi, Xinjiang Uygur Autonomous Region, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Lanzhou University

    Lanzhou, Gansu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital of Dalian Medical University

    Dalian, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Third Hospital of Hebei Medical University

    Shijiazhuang, Hebei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xuanwu Hospital Capital Medical University

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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