Blood test guides second round of targeted therapy for tough colorectal cancer
NCT ID NCT06578559
First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 24 times
Summary
This study tests whether people with a specific type of advanced colorectal cancer (BRAF V600E mutation) can benefit from a second round of a targeted drug combination (encorafenib plus cetuximab). Only patients who previously responded well to the same drugs are eligible, and a blood test is used to confirm the cancer still has the right genetic markers. The goal is to see how many patients have tumor shrinkage, while monitoring safety and how long the benefit lasts.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COLORECTAL CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
A.O.U. Citta Della Salute E Della Scienza Di Torino Presidio Molinette
Turin, TO, 10126, Italy
-
AUSL Romagna
Ravenna, RA, 48121, Italy
-
Azienda Ospedaliera Universitaria degli Studi di Campania L. Vanvitelli
Naples, 80131, Italy
-
Azienda Ospedaliero-Universitaria Pisana
Pisa, PI, 56126, Italy
-
Azienda Sanitaria Universitaria Friuli Centrale
Udine, UD, 33100, Italy
-
Fondazione Casa Sollievo Della Sofferenza - Irccs
San Giovanni Rotondo, FG, 71013, Italy
-
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, RM, 00168, Italy
-
IRCCS Istituto Nazionale dei Tumori di Milano
Milan, MI, 20133, Italy
-
Istituto Oncologico Veneto Irccs
Padova, PD, 35128, Italy
-
Istituto Romagnolo Per Lo Studio Dei Tumori "Dino Amadori" Irccs Irst
Meldola, FC, 47014, Italy
-
L'Azienda Ospedaliero Universitaria di Cagliari
Monserrato, CA, 09042, Italy
-
Nuovo Ospedale di Prato S. STEFANO
Prato, PO, 59100, Italy
-
Pia Fondazione di Culto e di Religione Cardinale G. Panico
Tricase, LE, 73039, Italy
Conditions
Explore the condition pages connected to this study.