Second chance: blood test guides retreatment for tough colorectal cancer
NCT ID NCT06578559
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for people with a certain genetic type of advanced colorectal cancer (BRAF V600E) who previously benefited from a specific drug combination (encorafenib plus cetuximab). Researchers want to see if giving these drugs again, guided by a blood test that looks for cancer DNA, can shrink tumors. The study involves 16 participants and uses CT scans every 8 weeks to check results.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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A.O.U. Citta Della Salute E Della Scienza Di Torino Presidio Molinette
Turin, TO, 10126, Italy
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AUSL Romagna
Ravenna, RA, 48121, Italy
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Azienda Ospedaliera Universitaria degli Studi di Campania L. Vanvitelli
Naples, 80131, Italy
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Azienda Ospedaliero-Universitaria Pisana
Pisa, PI, 56126, Italy
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Azienda Sanitaria Universitaria Friuli Centrale
Udine, UD, 33100, Italy
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Fondazione Casa Sollievo Della Sofferenza - Irccs
San Giovanni Rotondo, FG, 71013, Italy
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, RM, 00168, Italy
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IRCCS Istituto Nazionale dei Tumori di Milano
Milan, MI, 20133, Italy
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Istituto Oncologico Veneto Irccs
Padova, PD, 35128, Italy
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Istituto Romagnolo Per Lo Studio Dei Tumori "Dino Amadori" Irccs Irst
Meldola, FC, 47014, Italy
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L'Azienda Ospedaliero Universitaria di Cagliari
Monserrato, CA, 09042, Italy
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Nuovo Ospedale di Prato S. STEFANO
Prato, PO, 59100, Italy
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Pia Fondazione di Culto e di Religione Cardinale G. Panico
Tricase, LE, 73039, Italy