Simple breathing device may strengthen core and cut liver fat in seniors
NCT ID NCT07168733
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a 4-week program of inspiratory muscle training (using a device called POWERbreathe) could improve diaphragm and abdominal wall muscle thickness and reduce liver fat in healthy women aged 60-80. Twenty-six women were split into a training group and a control group. The training group did breathing exercises twice daily, five days a week. Researchers measured muscle thickness and liver fat before and after the program.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Inspiratory muscle training using the POWERbreathe® device
- What this could lead to
- If successful, this could point toward a simple, drug-free way to help older women maintain muscle strength and reduce liver fat.
- What could go wrong
- This is a very small, early study with only 26 participants, so results may not apply to everyone. The training lasted only 4 weeks, so long-term benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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26 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * were defined as women aged 60-80 years (post-menopausal), who were independent in activities of daily living, * demonstrated adequate cognitive function to follow instructions, * had no musculoskeletal injury within the previous six months, * were non-smokers, * had routine thoracic or abdominal CT images obtained for clinical indications and used in this study. Exclusion Criteria: * included having uncontrolled cardiovascular or pulmonary disease such as heart failure or COPD/asthma exacerbation, * uncontrolled hypertension, diagnosed chronic liver disease, * acute respiratory infection within the last four weeks, * participation in structured respiratory or resistance training within the last six months, * recent thoracoabdominal surgery or hernia, use of medications known to affect muscle or liver metabolism such as systemic corticosteroids, anabolic agents, or hepatotoxic drugs, * severe orthopedic or neurological conditions limiting mobility, or refusal to participate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gumushane Univetsity
Kelkit, Gümüşhane Province, 29600, Turkey (Türkiye)
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