New hope for keeping advanced breast cancer in check

NCT ID NCT05894239

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called inavolisib to standard maintenance therapy helps people with a specific type of advanced breast cancer live longer without their cancer getting worse. It will involve about 230 people whose cancer has spread and has two specific genetic markers (HER2-positive and PIK3CA-mutated). After initial treatment, participants will receive either the new combination or the standard therapy plus a placebo to see which is more effective at controlling the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Trento"
WITHDRAWN

Verona, Veneto, 37124, Italy
A.O.U. Maggiore della Carità
RECRUITING

Novara, Piedmont, 28100, Italy
Abderrahmen Mami Hospital
RECRUITING

Aryanah, 2080, Tunisia
Affiliated Hospital of Hebei University
RECRUITING

Baoding, 071000, China
Allan Blair Cancer Center
RECRUITING

Regina, Saskatchewan, S4T 7T1, Canada
Artemis Hospital
RECRUITING

Gurugram, Haryana, 122001, India
Arthur J.E. Child Comprehensive Cancer Center-Calgary
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Asan Medical Center
COMPLETED

Seoul, 05505, South Korea
Atrium Health
RECRUITING

Charlotte, North Carolina, 28209, United States
Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji
RECRUITING

Bakirkoy / Istanbul, 34147, Turkey (Türkiye)
Banner Health MD Anderson AZ
RECRUITING

Gilbert, Arizona, 85234, United States
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China
Belfast City Hospital
RECRUITING

Belfast, BT9 7AB, United Kingdom
Blackpool Victoria Hospital
RECRUITING

Blackpool, FY3 8NR, United Kingdom
Blacktown Hospital
RECRUITING

Blacktown, New South Wales, NSW 2148, Australia
CENEIT Oncologicos
RECRUITING

Mexico City, 03100, Mexico
CER San Juan Centro Polivalente de Asistencia e Investigacion Clinica
RECRUITING

San Juan, J5400DIL, Argentina
CHIREC
RECRUITING

Auderghem, 1160, Belgium
CHU Brugmann (Victor Horta)
RECRUITING

Brussels, 1020, Belgium
Caritas Klinik St. Theresia -Frauenklinik Brustzentrum
RECRUITING

Saarbrücken, 66113, Germany
Casa di Cura La Maddalena
RECRUITING

Palermo, Sicily, 90146, Italy
Centre Georges Francois Leclerc
RECRUITING

Dijon, 21000, France
Centre Hospitalier de La Cote Basque
RECRUITING

Bayonne, 64109, France
Centre Hospitalier de l?Université de Montréal (CHUM)
RECRUITING

Montreal, Quebec, PO 25223, Canada
Centre Oscar Lambret
RECRUITING

Lille, 59020, France
Centro Oncologico Korben
RECRUITING

Ciudad Autonoma Buenos Aires, C1426AGE, Argentina
Centro Oncológico Hematológico Roma
RECRUITING

Mexico City, Mexico CITY (federal District), 06700, Mexico
Centro de Investigaciones Médicas y Desarrollo LC S.R.L
ACTIVE_NOT_RECRUITING

Buenos Aires, Ciudad Autónoma de BuenosAires, C1113AAE, Argentina
Centrum Onkologii Instytut im.M. Sklodowskiej-Curie
RECRUITING

Warsaw, 02-781, Poland
Centrum Onkologii im. Prof. Franciszka ?ukaszczyka
RECRUITING

Bydgoszcz, 85-796, Poland
Chang Gung Memorial Hospital-Linkou
RECRUITING

Taoyuan, 333, Taiwan
Charlotte Maxeke Academic Hospital
RECRUITING

Johannesburg, 2193, South Africa
Chiba Cancer Center
RECRUITING

Chiba, 260-8717, Japan
Chris Hani Baragwanath Clinical Trial Site
ACTIVE_NOT_RECRUITING

Soweto, 2013, South Africa
Churchill Hospital
RECRUITING

Oxford, OX3 7LJ, United Kingdom
City of Hope
RECRUITING

Corona, California, 92882, United States
City of Hope Comprehensive Cancer Center
RECRUITING

Duarte, California, 91010, United States
City of Hope at Irvine Lennar
RECRUITING

Irvine, California, 92618, United States
Clinica De La Costa
WITHDRAWN

Barranquilla, 080020, Colombia
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda
RECRUITING

São Paulo, São Paulo, 01317-001, Brazil
Clinique Ste-Elisabeth
RECRUITING

Namur, 5000, Belgium
Cliniques Universitaires St-Luc
RECRUITING

Brussels, 1200, Belgium
Clínica Viedma
WITHDRAWN

Viedma Rio Negro, R8500ACE, Argentina
Colchester General Hospital
RECRUITING

Colchester, Essex, CO4 5JL, United Kingdom
Complejo Hospitalario Universitario A Coruña (CHUAC)
RECRUITING

A Coruña, LA Coruna, 15006, Spain
Crio - Centro Regional Integrado de Oncologia
RECRUITING

Fortaleza, Ceará, 60336-232, Brazil
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Dicle University Faculty of Medicine
RECRUITING

Diyarbakır, 21280, Turkey (Türkiye)
Disney Family Cancer Center
RECRUITING

Burbank, California, 91505, United States
Eastern Health - General Hospital
RECRUITING

St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Ellison Institute of Technology
RECRUITING

Los Angeles, California, 90064, United States
Farhat Hached Hospital
RECRUITING

Sousse, 4031, Tunisia
Frauenarztpraxis Dr. Apel, Dr. Kolpin
RECRUITING

Erfurt, 99084, Germany
Fujian Cancer Hospital
RECRUITING

Fuzhou, 350014, China
Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo
RECRUITING

Bogota, D.C., 110131, Colombia
GHdC Site Les Viviers
WITHDRAWN

Charleroi, 6000, Belgium
Gangnam Severance Hospital
ACTIVE_NOT_RECRUITING

Seoul, 06273, South Korea
Gazi University Medical Faculty
RECRUITING

Ankara, 06500, Turkey (Türkiye)
Georgetown Uni Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Gosford Hospital
RECRUITING

Gosford, New South Wales, 2250, Australia
Guangxi Cancer Hospital of Guangxi Medical University
ACTIVE_NOT_RECRUITING

Nanning, 530021, China
Gujarat Cancer & Research Inst.
RECRUITING

Ahmedabad, Gujarat, 380016, India
Gulhane Training and Research Hospital
RECRUITING

Ankara, 06010, Turkey (Türkiye)
Gynonco Düsseldorf, MVZ Medical Center GmbH
RECRUITING

Düsseldorf, 40235, Germany
Gynäkologie Kompetenzzentrum
WITHDRAWN

Stralsund, 18439, Germany
HELIOS Klinikum Berlin-Buch
RECRUITING

Berlin, 13125, Germany
Habib Bourguiba Hospital
RECRUITING

Sfax, 3029, Tunisia
Hacettepe Uni Medical Faculty Hospital
RECRUITING

Sihhiye/Ankara, 06230, Turkey (Türkiye)
Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Harbin Medical University Tumor Hospital
ACTIVE_NOT_RECRUITING

Harbin, 150049, China
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Hightower Clinical
WITHDRAWN

Oklahoma City, Oklahoma, 73102, United States
Hiroshima City Hiroshima Citizens Hospital
RECRUITING

Hiroshima, 730-8518, Japan
Hopelands Cancer Centre
RECRUITING

Hilton, 3245, South Africa
Hopital du Saint Sacrement
RECRUITING

Québec, Quebec, G1S 4L8, Canada
Hospital Araujo Jorge
RECRUITING

Goiânia, Goiás, 74605-070, Brazil
Hospital Civil de Guadalajara Fray Antonio Alcalde
RECRUITING

Guadalajara, Jalisco, 44280, Mexico
Hospital Clinico Universitario Virgen de la Victoria
RECRUITING

Málaga, 29010, Spain
Hospital General Universitario Gregorio Marañon
RECRUITING

Madrid, 28007, Spain
Hospital Provincial del Centenario
RECRUITING

Rosario, S2002KDS, Argentina
Hospital Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Sao Lucas - PUCRS
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Hospital Sao Rafael - HSR
RECRUITING

Salvador, Estado de Bahia, 41253-190, Brazil
Hospital Universitari Dexeus - Grupo Quironsalud
RECRUITING

Barcelona, 08028, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario
WITHDRAWN

Monterrey, Nuevo León, 64460, Mexico
Hospital Universitario 12 de Octubre
ACTIVE_NOT_RECRUITING

Madrid, 28041, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hospital de Amor Amazônia
RECRUITING

Porto Velho, Rondônia, 76834-899, Brazil
Hospital de Cancer de Barretos
RECRUITING

Barretos, São Paulo, 14784-400, Brazil
Hospital do Cancer de Pernambuco - HCP
RECRUITING

Recife, Pernambuco, 50040-000, Brazil
Hospital do Câncer de Londrina
RECRUITING

Londrina, Paraná, 86015-520, Brazil
Hubei Cancer Hospital
RECRUITING

Wuhan, 430079, China
Hôpital du Sacré-Coeur de Montreal
RECRUITING

Montreal, Quebec, H4J 1C5, Canada
I.R.S.T Srl IRCCS
RECRUITING

Meldola, Emilia-Romagna, 47014, Italy
Icon Cancer Centre Farrer Park
WITHDRAWN

Singapore, 217562, Singapore
Institut Jules Bordet
RECRUITING

Anderlecht, 1070, Belgium
Institut Sainte Catherine
RECRUITING

Avignon, 84082, France
Institut Salah Azeiz
RECRUITING

Tunis, 1006, Tunisia
Instituto de Oncología de Rosario
RECRUITING

Rosario, S2000KZE, Argentina
Instituto do Cancer do Estado de Sao Paulo - ICESP
RECRUITING

São Paulo, São Paulo, 01246-000, Brazil
Irccs Istituto Europeo Di Oncologia (IEO)
RECRUITING

Milan, Lombardy, 20141, Italy
Irccs Istituto Nazionale Dei Tumori (Int)
RECRUITING

Milan, Lombardy, 20133, Italy
JPS Health Network
RECRUITING

Fort Worth, Texas, 76104, United States
Jessa Zkh (Campus Virga Jesse)
RECRUITING

Hasselt, 3500, Belgium
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Kadlec Clinic Hematology and Oncology
RECRUITING

Kennewick, Washington, 99336-7774, United States
Katip Celebi University Ataturk Training and Research Hospital
RECRUITING

Izmir, 35360, Turkey (Türkiye)
King Hussein Cancer Center
RECRUITING

Amman, 11941, Jordan
Kinghorn Cancer Centre
RECRUITING

Darlinghurst, New South Wales, 2010, Australia
Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt
RECRUITING

München, 80336, Germany
Klinikum St. Marien
RECRUITING

Amberg, 92224, Germany
Limpopo Cancer Research Institute
RECRUITING

Polokwane, 0700, South Africa
Lumi Research
WITHDRAWN

Kingwood, Texas, 77339, United States
Marienhospital Bottrop gGmbH
RECRUITING

Bottrop, 46236, Germany
Max Super Speciality Hospital
RECRUITING

NEW Delhi Delhi, National Capital Territory of Delhi, 110092, India
Medical Oncology Centre of Rosebank
RECRUITING

Johannesburg, 2196, South Africa
Medical Park Seyhan Hospital
ACTIVE_NOT_RECRUITING

Seyhan, 01140, Turkey (Türkiye)
Medipol Mega Üniversite Hastanesi Göztepe
RECRUITING

Istanbul, 34214, Turkey (Türkiye)
Medstar Research Institute
RECRUITING

Hyattsville, Maryland, 20783, United States
Monash Health
RECRUITING

Clayton, Victoria, 3168, Australia
Mount Vernon Hospital
RECRUITING

Northwood, HA6 2RN, United Kingdom
Narodowy Instytut Onkologii Odzia? w Gliwicach
RECRUITING

Gliwice, 44-102, Poland
National Cancer Center
ACTIVE_NOT_RECRUITING

Goyang-si, 10408, South Korea
National Cancer Centre
ACTIVE_NOT_RECRUITING

Singapore, 169610, Singapore
National Cancer Institute
RECRUITING

Nagpur, Maharashtra, 441108, India
National Taiwan Uni Hospital
RECRUITING

Taipei, 100, Taiwan
National University Hospital
RECRUITING

Singapore, 119228, Singapore
Nottingham City Hospital
RECRUITING

Nottingham, NG5 1PB, United Kingdom
OncoMed
RECRUITING

Mexico City, Mexico CITY (federal District), 03100, Mexico
Oncomedica S.A.
RECRUITING

Montería, 230002, Colombia
Ospedale San Gerardo
RECRUITING

Monza, Lombardy, 20900, Italy
Ospedale San Giovanni Addolorata
RECRUITING

Rome, Lazio, 00185, Italy
Ospedale San Raffaele
RECRUITING

Milan, Lombardy, 20132, Italy
Ospedale Santa Maria Annunziata
RECRUITING

Bagno a Ripoli, Tuscany, 50012, Italy
Polyclinique Bordeaux Nord Aquitaine
RECRUITING

Bordeaux, 33300, France
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR
RECRUITING

Freiburg im Breisgau, 79110, Germany
Przychodnia Lekarska KOMED, Roman Karaszewski
RECRUITING

Konin, 62-500, Poland
Queen Mary Hospital
RECRUITING

Hong Kong, Hong Kong
Renovatio Clinical
RECRUITING

The Woodlands, Texas, 77380, United States
Renovatio Clinical - El Paso
RECRUITING

El Paso, Texas, 79915, United States
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
Sagara Hospital
RECRUITING

Kagoshima, 892-0833, Japan
Saitama Medical University International Medical Center
RECRUITING

Saitama, 350-1298, Japan
Sakarya Training and Research Hospital
RECRUITING

Adapazarı, 54290, Turkey (Türkiye)
Samsung Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 06351, South Korea
Santa Casa de Misericordia de Porto Alegre
ACTIVE_NOT_RECRUITING

Porto Alegre, Rio Grande do Sul, 90050-170, Brazil
Seoul National University Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Seoul St Mary's Hospital
ACTIVE_NOT_RECRUITING

Seoul, 06591, South Korea
Severance Hospital, Yonsei University Health System
ACTIVE_NOT_RECRUITING

Seoul, 03722, South Korea
Shandong Cancer Hospital
RECRUITING

Jinan, 250117, China
Shantou Center Hospital
RECRUITING

Shantou, 515031, China
Sichuan Provincial Cancer Hospital
RECRUITING

Chengdu, 610041, China
Sichuan Provincial People's Hospital
ACTIVE_NOT_RECRUITING

Chengdu, 610072, China
Sir Charles Gairdner Hospital
RECRUITING

Perth, Western Australia, 6009, Australia
Sir H. N. Reliance Foundation Hospital and Research Centre
RECRUITING

Mumbai, Maharashtra, 400004, India
Sociedad de Oncología y hematología del Cesar Ltda
RECRUITING

Valledupar, 200001, Colombia
St. Franziskus Hospital Münster;Studiensekretariat der onkologischen Zentren
RECRUITING

Münster, 48145, Germany
Steve Biko Academic Hospital
RECRUITING

Pretoria, 0002, South Africa
Sultan Qaboos Comprehensive Cancer Care & Research Center
RECRUITING

Muscat, Oman
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Sunshine Global Hospital (A unit of Baroda Medicare Pvt Ltd)
RECRUITING

Surat, Gujarat, 395007, India
Swedish Medical Center
RECRUITING

Seattle, Washington, 98104-1360, United States
Szpital Morski im.PCK
RECRUITING

Gdynia, 81-519, Poland
Szpital Wojewódzki im. Miko?aja Kopernika
RECRUITING

Koszalin, 75-581, Poland
Taher Maamouri Hospital
RECRUITING

Nabeul, 8000, Tunisia
Tampere University Hospital
RECRUITING

Tampere, 33520, Finland
Tan Tock Seng Hospital
WITHDRAWN

Singapore, 308433, Singapore
Tata Medical Center
RECRUITING

Kolkata, West Bengal, 700160, India
The Cancer Institute Hospital of JFCR
RECRUITING

Tokyo, 135-8550, Japan
The First Affiliated Hospital to Henan University of Science and Technology
RECRUITING

Luoyang, 471003, China
The First Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Moncton Hospital
RECRUITING

Moncton, New Brunswick, E1C 6Z8, Canada
The Second Affiliated Hospital to Nanchang University
ACTIVE_NOT_RECRUITING

Nanchang, 330006, China
Tianjin Cancer Hospital
RECRUITING

Tianjin, 300000, China
Tri-Service General Hospital
RECRUITING

Taipei, Taiwan
Tuen Mun Hospital
RECRUITING

Hong Kong, Hong Kong
Turku Uni Central Hospital
RECRUITING

Turku, 20520, Finland
Uganda Cancer Institute
RECRUITING

Kampala, 00256, Uganda
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, 430022, China
University of Nairobi - Institute of Tropical and Infectious Diseases
RECRUITING

Nairobi, Kenya
University of the Sunshine Coast
RECRUITING

Sippy Downs, Queensland, 4556, Australia
Universitätsfrauenklinik Ulm
RECRUITING

Ulm, 89075, Germany
Universitätsklinikum Erlangen
RECRUITING

Erlangen, 91054, Germany
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gda?sk, 80-214, Poland
Wielkopolskie Centrum Onkologii im. Marii Sk?odowskiej-Curie
RECRUITING

Późna, 61-866, Poland
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, 310022, China

Conditions

Explore the condition pages connected to this study.

METASTATIC BREAST CANCER