New Triple-Threat treatment trial targets advanced breast cancer

NCT ID NCT06790693

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called inavolisib to two standard breast cancer medications works better than the standard two-drug combination alone. It's for people with advanced breast cancer that has a specific genetic change (PIK3CA mutation) and is sensitive to hormone-blocking therapy. The goal is to see if this three-drug combination can better control the cancer's growth and improve survival.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A.O. S. Anna e San Sebastiano
RECRUITING

Caserta, Campania, 81100, Italy
A.O. Santa Maria Terni
RECRUITING

Terni, Umbria, 05100, Italy
A.O. Universitaria Federico II Di Napoli
RECRUITING

Naples, Campania, 80131, Italy
A.O. Universitaria Policlinico Di Modena
RECRUITING

Modena, Emilia-Romagna, 41100, Italy
Abdurrahman Yurtarslan Onkoloji Training and Research Hospital
RECRUITING

Ankara, 06200, Turkey (Türkiye)
Abraham Oncology
RECRUITING

Richards Bay, 3900, South Africa
Ankara City Hospital
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde
RECRUITING

Guadalajara, 44280, Mexico
Arthur J.E. Child Comprehensive Cancer Center
RECRUITING

Calgary, Alberta, T2N 4C2, Canada
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Asst Papa Giovanni XXIII
RECRUITING

Bergamo, Lombardy, 24127, Italy
Astera Cancer Care East Brunswick
RECRUITING

East Brunswick, New Jersey, 08816, United States
Az. Osp. G. Panico
RECRUITING

Tricase (LE), Apulia, 73039, Italy
Azienda Sanitaria dell'Alto Adige;U.O.C. Oncologia Medic
RECRUITING

Bolzano, Trentino-Alto Adige, 39100, Italy
Ba?c?lar Medipol Mega Üniversite Hastanesi
RECRUITING

Istanbul, 34214, Turkey (Türkiye)
Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji
RECRUITING

Bakirkoy / Istanbul, 34147, Turkey (Türkiye)
Baptist Health Hamburg
RECRUITING

Lexington, Kentucky, 40509, United States
Baptist Health Lexington
RECRUITING

Lexington, Kentucky, 40503, United States
Baptist Health Louisville
RECRUITING

Louisville, Kentucky, 40207, United States
Bialostockie Centrum Onkologii
RECRUITING

Bialystok, 15-027, Poland
Blackpool Victoria Hospital
RECRUITING

Blackpool, FY3 8NR, United Kingdom
Bon Secours - St. Francis Hospital
RECRUITING

Greenville, South Carolina, 29607, United States
CHUV
RECRUITING

Lausanne, 1011, Switzerland
COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej
RECRUITING

Lublin, 20-090, Poland
Cancer & Hematology Centers of Western Michigan
RECRUITING

Grand Rapids, Michigan, 49503, United States
Cancer Care Specialists of Central Illinois
RECRUITING

O'Fallon, Illinois, 62269, United States
Cancer and Blood Specialty Clinic
RECRUITING

Los Alamitos, California, 90720, United States
CancerCare Manitoba
RECRUITING

Winnipeg, Manitoba, R3E 0V9, Canada
Caritas Klinik St. Theresia -Frauenklinik Brustzentrum
RECRUITING

Saarbrücken, 66113, Germany
Caritas-Krankenhaus St. Josef
RECRUITING

Regensburg, 93053, Germany
Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States
Centre CARIO - HPCA
RECRUITING

Plérin, 22190, France
Centre Cancerologie Grand Montpellier
RECRUITING

Montpellier, 34070, France
Centre Eugene Marquis
RECRUITING

Rennes, 35042, France
Centre Henri Becquerel
RECRUITING

Rouen, 76038, France
Centre Hospitalier de l'Universite de Montreal (CHUM)
RECRUITING

Montreal, Quebec, H2X 0C1, Canada
Centre Oscar Lambret
RECRUITING

Lille, 59020, France
Centro Estatal de Cancerologia de Chihuahua
RECRUITING

Chihuahua City, 31000, Mexico
Centro Médico Fleischer
RECRUITING

Capital Federal, C1414, Argentina
Centro Oncologico Korben
RECRUITING

Caba, C1426AGE, Argentina
Centro Oncológico de Excelencia
RECRUITING

San Juan, J5400, Argentina
Centro de Investigacion Clinica de Oaxaca
RECRUITING

Oaxaca City, Oaxaca, 68020, Mexico
Centro de Investigacion y Tratamiento Integral del Cancer: CITI Cancer Oaxaca S.A de C.V.
RECRUITING

Ciudad de Huajuapan de León, Oaxaca, 69007, Mexico
Centro de Oncologia de Alfenas
RECRUITING

Alfenas, Minas Gerais, 37130-087, Brazil
Chia-Yi Christian Hospital
RECRUITING

Chiayi City, 600566, Taiwan
Chiba Cancer Center
RECRUITING

Chiba, 260-8717, Japan
Chu La Miletrie
RECRUITING

Poitiers, 86021, France
Churchill Hospital - Oxford Cancer & Haematology Centre
RECRUITING

Oxford, OX3 7LE, United Kingdom
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44915, United States
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda
RECRUITING

São Paulo, São Paulo, 01317-001, Brazil
Community Clinical Trials
RECRUITING

Kingwood, Texas, 77339, United States
Crio - Centro Regional Integrado de Oncologia
RECRUITING

Fortaleza, Ceará, 60336-232, Brazil
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
Disney Family Cancer Center
RECRUITING

Burbank, California, 91505, United States
Dolno?l?skie Centrum Onkologii
RECRUITING

Wroc?aw, 53-413, Poland
Dres. Andreas Köhler und Roswitha Fuchs
RECRUITING

Langen, 63225, Germany
Ellison Institute of Technology
RECRUITING

Los Angeles, California, 90064, United States
Fairview Hospital
RECRUITING

Cleveland, Ohio, 44111, United States
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Rome, Lazio, 00168, Italy
Fukushima Medical University Hospital
RECRUITING

Fukushima, 960-1295, Japan
Fundacion Instituto Valenciano de Oncologia (IVO)
RECRUITING

Valencia, 46009, Spain
Gangnam Severance Hospital
RECRUITING

Seoul, 06273, South Korea
Guangxi Cancer Hospital of Guangxi Medical University
RECRUITING

Nanning, 530021, China
Gustave Roussy
RECRUITING

Villejuif, 94805, France
HCA Midwest Health
RECRUITING

Kansas City, Missouri, 64132, United States
HOPITAL RENE HUGUENIN- Institut Curie
RECRUITING

Saint-Cloud, 92211, France
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, 150081, China
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Hillcrest Hospital
RECRUITING

Mayfield Heights, Ohio, 44124, United States
Hokkaido University Hospital
RECRUITING

Hokkaido, 060-8648, Japan
Hospital Araujo Jorge
RECRUITING

Goiânia, Goiás, 74605-070, Brazil
Hospital Clinico Universitario Virgen de la Victoria;Servicio de Oncologia
RECRUITING

Málaga, 29011, Spain
Hospital Clinico Universitario de Valencia
RECRUITING

Valencia, 46010, Spain
Hospital General Univ. Gregorio Maranon
RECRUITING

Madrid, 28009, Spain
Hospital General Universitario de Elche
RECRUITING

Elche, Alicante, 03203, Spain
Hospital General de Mexico
RECRUITING

MexicoCiudad de México, Nuevo León, 6726, Mexico
Hospital Privado Centro Medico de Cordoba
RECRUITING

Córdoba, 5016, Argentina
Hospital Santa Rita de Cassia Vitoria
RECRUITING

Vitória, Espírito Santo, 29043-260, Brazil
Hospital Universitario 12 De Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Clínico San Carlos
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Infanta Leonor
RECRUITING

Madrid, 28031, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitario de la Princesa
RECRUITING

Madrid, 28006, Spain
Hospital Zambrano Hellion TecSalud
RECRUITING

Monterrey, Nuevo León, Mexico
Hospital de Basurto
RECRUITING

Bilbao, Vizcaya, 48013, Spain
Hospital de Cancer de Barretos
RECRUITING

Barretos, São Paulo, 14784-400, Brazil
Hospital de Navarra
RECRUITING

Pamplona/iruña, Navarre, 31008, Spain
Hospital do Cancer de Pernambuco - HCP
RECRUITING

Recife, Pernambuco, 50040-000, Brazil
Hospital do Câncer de Londrina
RECRUITING

Londrina, Paraná, 86015-520, Brazil
Humanitas Centro Catanese Di Oncologia
RECRUITING

Misterbianco (CT), Sicily, 95045, Italy
Hunan Cancer Hospital
RECRUITING

Changsha, 410013, China
Hôpital du Sacré-Coeur de Montreal
RECRUITING

Montreal, Quebec, H4J 1C5, Canada
ICO L'Hospitalet
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08908, Spain
INSTITUT CURIE_SITE PARIS - Service d'Oncologie Médicale.
RECRUITING

Paris, 75005, France
IOB Madrid Institute of Oncology Hospital Beata Maria Ana de Jesus;Unidad Central de Oncología Médica y de Investigación Oncológica
RECRUITING

Madrid, 28007, Spain
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola
RECRUITING

Meldola, Emilia-Romagna, 47014, Italy
Ico Rene Gauducheau
RECRUITING

Saint-Herblain, 44805, France
Iem-Fucam
RECRUITING

D.F., 04980, Mexico
InVO - Institut für Versorgungsforschung in der Onkologie GbR
RECRUITING

Koblenz, 56068, Germany
Institut Universitaire de Cancer de Toulouse Oncopole
RECRUITING

Toulouse, 31100, France
Instituto Nacional De Cancerologia
RECRUITING

Distrito Federal, Mexico CITY (federal District), 14000, Mexico
Instituto Nacional de Cancer - INCa
RECRUITING

Rio de Janeiro, 20560-120, Brazil
Instituto de Oncologia de Rosario
RECRUITING

Rosario, S2013KZE, Argentina
Instituto do Cancer do Estado de Sao Paulo - ICESP
RECRUITING

São Paulo, São Paulo, 01246-000, Brazil
Instytut "Centrum Zdrowia Matki Polki"
RECRUITING

?ód?, 93-338, Poland
Irccs Istituto Nazionale Dei Tumori (Int)
RECRUITING

Milan, Lombardy, 20133, Italy
Istituto Clinico Humanitas
RECRUITING

Rozzano, Lombardy, 20089, Italy
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Jiangmen Central Hospital
RECRUITING

Jiangmen, 529030, China
Jinhua municipal central hospital
RECRUITING

Jinhua, 321083, China
Kaiser Permanente - San Marcos
RECRUITING

San Marcos, California, 92069, United States
Kanagawa Cancer Center
RECRUITING

Kanagawa, 241-8515, Japan
Kantonsspital Baden Zentrum für Onkologie und Hämatologie
RECRUITING

Baden, 5404, Switzerland
Katip Celebi University Ataturk Training and Research Hospital
RECRUITING

Izmir, 35360, Turkey (Türkiye)
Klinikum Ernst von Bergmann
RECRUITING

Potsdam, 14467, Germany
Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH
RECRUITING

Essen, 45136, Germany
Koo Foundation Sun Yat-Sen Cancer Center
RECRUITING

Taipei, 112019, Taiwan
Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem
RECRUITING

Hamburg, 20357, Germany
Kyungpook National University Chilgok Hospital
RECRUITING

Daegu, 41404, South Korea
Linksfield Oncology Inc.
RECRUITING

Johannesburg, 2192, South Africa
Luzerner Kantonsspital
RECRUITING

Lucerne, 6004, Switzerland
Lyell McEwin Hospital
RECRUITING

Elizabeth Vale, South Australia, 5112, Australia
MRUKMED Lekarz Beata Madej-Mruk i Partner Spolka Partnerska Oddzial nr 1 w Rzeszowie
RECRUITING

Rzeszów, 35-021, Poland
Medizinische Hochschule Zentrum Frauenheilkunde Abt.Gynäkologische Onkologie
RECRUITING

Hanover, 30625, Germany
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Mersin City Education and Research Hospital
RECRUITING

Mersin, 33240, Turkey (Türkiye)
Moffitt Cancer Center-McKinley Campus
RECRUITING

Tampa, Florida, 33612, United States
Mount Vernon & Watford Hospital Trust
RECRUITING

Northwood, HA6 2RN, United Kingdom
Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad
RECRUITING

Warsaw, 02-781, Poland
National Cancer Center
RECRUITING

Goyang-si, 10408, South Korea
National Cheng Kung Uni Hospital
RECRUITING

Tainan, 704, Taiwan
National Taiwan Uni Hospital
RECRUITING

Taipei, 100, Taiwan
Nationales Centrum für Tumorerkrankungen (NCT)
RECRUITING

Heidelberg, 69120, Germany
Nebraska Cancer Specialists
RECRUITING

Grand Island, Nebraska, 68803, United States
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130-2042, United States
Northwest Georgia Oncology Centers PC - Marietta
RECRUITING

Marietta, Georgia, 30060, United States
Northwest Medical Specialties
RECRUITING

Tacoma, Washington, 98405, United States
Obras Sociais Irma Dulce - Osid
RECRUITING

Salvador, Estado de Bahia, 40415-006, Brazil
Ospedale Civile - Livorno
RECRUITING

Livorno, Tuscany, 57124, Italy
Ospedale San Raffaele
RECRUITING

Milan, Lombardy, 20132, Italy
Palo Alto Medical Foundation Research Center
RECRUITING

Palo Alto, California, 94301, United States
Palo Alto Medical Foundation Research Center
RECRUITING

San Mateo, California, 94401, United States
Palo Alto Medical Foundation Research Center
RECRUITING

Sunnyvale, California, 94086, United States
PanOncology Trials
RECRUITING

San Juan, 00935, Puerto Rico
Peking Union Medical College Hospital
RECRUITING

Beijing, 100032, China
Policlinico S.Orsola-Malpighi
RECRUITING

Bologna, Emilia-Romagna, 40138, Italy
Princess Alexandra Hospital
RECRUITING

Harlow, CM20 1QX, United Kingdom
Providence Oncology and Hematology Cancer Clinic - Westside;Investigation Drug Services Pharmacy
RECRUITING

Portland, Oregon, 97225, United States
Providence Portland Medical Center
RECRUITING

Portland, Oregon, 97213, United States
Providence Regional Cancer Partnership
RECRUITING

Everett, Washington, 98201-1621, United States
Przychodnia Lekarska KOMED, Roman Karaszewski
RECRUITING

Konin, 62-500, Poland
Royal Free Hospital
RECRUITING

London, NW3 2QG, United Kingdom
Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia
Saitama Medical University International Medical Center
RECRUITING

Saitama, 350-1298, Japan
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Santa Casa de Misericordia de Porto Alegre
RECRUITING

Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Sault Area Hospital
RECRUITING

Sault Ste. Marie, Ontario, P6B 0A8, Canada
Scripps Health
RECRUITING

La Jolla, California, 92040, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, 463-707, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shandong Cancer Hospital
RECRUITING

Jinan, 250117, China
Shantou Center Hospital
RECRUITING

Shantou, 515031, China
Shanxi Provincial People's Hospital
RECRUITING

Xi'an, 710068, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, 610072, China
Soon Chun Hyang University Cheonan Hospital
RECRUITING

Dongnam-gu, Cheonan-si, 31151, South Korea
Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States
St Bartholomew's Hospital
RECRUITING

London, EC1M 6BQ, United Kingdom
St. Elisabeth Krankenhaus Köln GmbH
RECRUITING

Cologne, 50935, Germany
St. Joseph's Health Centre
RECRUITING

Toronto, Ontario, M6R 1B5, Canada
Summit Medical Group
RECRUITING

Florham Park, New Jersey, 07932, United States
Sun Yat-Sen University Cancer Center - Huangpu Campus
RECRUITING

Guangzhou, China
Sun yat-sen University Cancer Center
RECRUITING

Guangzhou, 510060, China
Swedish Cancer Institute
RECRUITING

Seattle, Washington, 98104, United States
Swedish Cancer Institute - Edmonds Campus
RECRUITING

Edmonds, Washington, 98026, United States
Swedish Cancer Institute - Issaquah
RECRUITING

Seattle, Washington, 98104, United States
Szpital Miejski Specjalistyczny Narutowicza
RECRUITING

Krakow, 31-202, Poland
Szpital Wojewódzki im. Miko?aja Kopernika
RECRUITING

Koszalin, 75-581, Poland
Taichung Veterans General Hospital
RECRUITING

Taichung, 407219, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 112201, Taiwan
Tallahassee Memorial HealthCare
RECRUITING

Tallahassee, Florida, 32308, United States
The Cancer Inst. Hosp. of JFCR
RECRUITING

Tokyo, 135-8550, Japan
The Moncton Hospital
RECRUITING

Moncton, New Brunswick, E1C 6Z8, Canada
The Ottawa Hospital Cancer Center
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
The Second Affiliated Hospital of Xi'an Jiao Tong University
RECRUITING

Xi'an, 710004, China
Tianjin Cancer Hospital
RECRUITING

Tianjin, 300000, China
Tianjin Cancer hospital Airport hospital
RECRUITING

Tianjin, 300300, China
U.O.C. Oncologia Medica Senologica
RECRUITING

Naples, Campania, 80131, Italy
Unité de Recherche Clinique du CISSS de Laurentides
RECRUITING

Saint-Jérôme, Quebec, J7Z 2V4, Canada
University of Eastern Piedmont - Maggiore della Carità University Hospital
RECRUITING

Novara, Umbria, 28100, Italy
University of Kentucky - Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States
Universitätsklinik Tübingen
RECRUITING

Tübingen, 72076, Germany
Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden
RECRUITING

Dresden, 01307, Germany
Universitätsklinikum Essen
RECRUITING

Essen, 45122, Germany
Universitätsklinikum Münster
RECRUITING

Münster, 48149, Germany
Universitätsklinikum Ulm Am Michelsberg
RECRUITING

Ulm, 89075, Germany
Universitätsspital Basel
RECRUITING

Basel, 4031, Switzerland
Vall d'Hebron Institute of Oncology (VHIO), Barcelona
RECRUITING

Barcelona, 08035, Spain
Velocity Clinical Research
RECRUITING

Annapolis, Maryland, 21401, United States
Vencer Oncoclínica - Centro de Pesquisa do Piauí
RECRUITING

Teresina, Piauí, 64049-200, Brazil
West Cancer Center
RECRUITING

Germantown, Tennessee, 38138, United States
West China Hospital of Sichuan University
RECRUITING

Chengdu, 610041, China
Western General Hospital
RECRUITING

Edinburgh, EH4 2XU, United Kingdom
Weston Park Hospital
RECRUITING

Sheffield, S10 2SJ, United Kingdom
Wielkopolskie Centrum Onkologii im. Marii Sk?odowskiej-Curie
RECRUITING

Późna, 61-866, Poland
Wits Clinical Research
RECRUITING

Soweto, 2013, South Africa
Xiangyang Central Hospital
RECRUITING

Xiangyang, Hubei, 441106, China
Xinjiang Medical University Cancer Hospital
RECRUITING

Ürümqi, 830011, China
Yunnan Cancer Hospital
RECRUITING

Kunming, 650118, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, 310022, China

Conditions

Explore the condition pages connected to this study.

BREAST CANCER