New drug combo tested to keep advanced breast cancer in check

NCT ID NCT05392608

Summary

This study is testing if adding a drug called alpelisib to the standard hormone therapy fulvestrant can help control advanced breast cancer that has started to grow again on fulvestrant alone. It is for adults whose cancer is hormone-receptor positive, HER2 negative, and has a specific genetic change (PIK3CA mutation). The main goal is to see if this combination can delay the cancer from progressing further.

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Contacts and locations

Locations

  • Admiraal de Ruyter Ziekenhuis

    Goes, Netherlands

  • Amphia

    Breda, Netherlands

  • Amsterdam UMC

    Amsterdam, Netherlands

  • Antoni van Leeuwenhoek

    Amsterdam, Netherlands

  • Canisius Wilhelmina Ziekenhuis

    Nijmegen, Netherlands

  • Deventer ziekenhuis

    Deventer, Netherlands

  • Elisabeth-TweeSteden Ziekenhuis

    Tilburg, Netherlands

  • Franciscus Gasthuis & Vlietland

    Schiedam, Netherlands

  • Gelre Ziekenhuizen

    Apeldoorn, Netherlands

  • HagaZiekenhuis

    The Hague, Netherlands

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, Netherlands

  • Maasstad Ziekenhuis

    Rotterdam, Netherlands

  • Martini Ziekenhuis

    Groningen, Netherlands

  • Meander Medisch Centrum

    Amersfoort, Netherlands

  • Medisch Centrum Leeuwarden

    Leeuwarden, Netherlands

  • Medisch Spectrum Twente

    Enschede, Netherlands

  • Máxima Medisch Centrum

    Eindhoven, Netherlands

  • Noordwest Ziekenhuisgroep

    Alkmaar, Netherlands

  • Reinier de Graaf Gasthuis

    Delft, Netherlands

  • Rijnstate

    Arnhem, Netherlands

  • Spaarne Gasthuis

    Hoofddorp, Netherlands

  • St. Antonius Ziekenhuis

    Nieuwegein, Netherlands

  • VieCuri Medisch Centrum

    Venlo, Netherlands

  • Ziekenhuis Amstelland

    Amstelveen, Netherlands

  • Ziekenhuisgroep Twente

    Almelo, Netherlands

Conditions

Explore the condition pages connected to this study.