New drug combo aims to boost breast cancer remission before surgery

NCT ID NCT07317778

First seen Jan 09, 2026 · Last updated May 10, 2026 · Updated 31 times

Summary

This study tests whether adding the immunotherapy drug adebrelimab and/or the targeted drug SHR-A1811 to standard chemotherapy can help more people with HR-positive, HER2-low early breast cancer achieve a complete response (no cancer found at surgery). About 249 participants will receive either standard chemo alone, chemo plus adebrelimab, or a sequence of SHR-A1811 plus adebrelimab followed by chemo plus adebrelimab. The goal is to see if the new combinations are more effective and safe.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Cancer Center/Cancer hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

    Beijing, 100021, China

Conditions

Explore the condition pages connected to this study.