New combo therapy aims to control advanced breast cancer with fewer side effects

NCT ID NCT03264547

Summary

This completed Phase 3 trial tested whether a new drug combination (eribulin + pertuzumab + trastuzumab) could control advanced HER2-positive breast cancer as well as the standard treatment (taxane + pertuzumab + trastuzumab), but with better quality of life. It involved 446 women with advanced or returning breast cancer who hadn't received certain prior chemotherapies. The main goal was to see if the new combination kept the cancer from worsening for a similar length of time while reducing side effects like numbness and tingling.

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Contacts and locations

Locations

  • Kanagawa Cancer Center

    Yokohama, Kanagawa, 241-8515, Japan

  • National Hospital Organization Osaka National Hospital

    Osaka, Osaka, 540-0006, Japan

Conditions

Explore the condition pages connected to this study.