New PET tracer could reveal hidden breast cancer activity

NCT ID NCT03083288

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This early-phase study tests a new PET imaging agent called 18F-FluorThanatrace (FTT) to measure a protein called PARP-1 in breast cancer tumors. About 30 adults with known or suspected breast cancer will receive an FTT PET/CT scan before surgery or treatment. Some may get a second scan after starting therapy to see how the tumor responds. The goal is to learn whether this scan can help doctors better see and monitor breast cancer, not to treat it.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.