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Can a simple test predict breast Cancer's next move?

NCT ID NCT07372261

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Casa Sollievo della Sofferenza IRCCS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new tool called PORTENT that uses tumor samples and patient history to estimate the risk of breast cancer spreading (metastasis) in people with early-stage disease. Researchers will analyze tissue from 1000 patients and track their health for up to 10 years. The goal is to see if the algorithm can accurately identify who is most likely to develop distant metastases, which could guide more personalized monitoring and treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a more accurate tool to predict which early-stage breast cancer patients are at risk of metastasis, helping tailor follow-up care.
What could go wrong
This is an observational study, not a treatment trial. The algorithm may not prove accurate enough for widespread use, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER EARLY STAGE BREAST CANCER (STAGE 1-3)

Contacts and locations

Locations

  • Fondazione Casa Sollievo della Sofferenza IRCCS

    San Giovanni Rotondo, FG, 71013, Italy

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