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New hope for advanced breast cancer: two hormone therapies face off in major trial

NCT ID NCT01602380

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This completed Phase 3 trial compared two hormone treatments for postmenopausal women with advanced breast cancer that responds to hormones. The study involved 462 women who hadn't received prior hormone therapy, randomly assigning them to receive either fulvestrant or anastrozole. Researchers measured which treatment better delayed cancer progression and improved survival while monitoring side effects and quality of life.

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Contacts and locations

Locations

  • Research Site

    Modesto, California, 95355, United States

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    Savannah, Georgia, 31405, United States

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    Auburn, Maine, 04212, United States

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    Worcester, Massachusetts, 01608, United States

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    Detroit, Michigan, 48202, United States

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    St Louis, Missouri, 63110, United States

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    Lincoln, Nebraska, 68506, United States

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    Somerset, New Jersey, 08873, United States

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    Columbus, Ohio, 43202, United States

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    Montgomery, Ohio, 45242, United States

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    Memphis, Tennessee, 38120, United States

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    Salt Lake City, Utah, 84107, United States

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    La Rioja, 5300, Argentina

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    Mar del Plata, B7600CTO, Argentina

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    Pergamino, B2700CPM, Argentina

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    Rosario, S2000KZE, Argentina

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    Porto Alegre, 91350-200, Brazil

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    Santo André, 09060-870, Brazil

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    Abbotsford, British Columbia, V2S0C2, Canada

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    Vancouver, British Columbia, V5Z 4E6, Canada

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    Kitchener, Ontario, N2G 1G3, Canada

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    Thunder Bay, Ontario, P7B 6V4, Canada

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    Montreal, Quebec, H3T 1E2, Canada

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    Montreal, Quebec, H4A 3J1, Canada

  • Research Site

    Chengdu, 610041, China

  • Research Site

    Dalian, 116011, China

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    Fuzhou, 350025, China

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    Guangzhou, 510060, China

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    Shanghai, 200032, China

  • Research Site

    Shenyang, 110001, China

  • Research Site

    Suzhou, 215004, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Prague, 150 06, Czechia

  • Research Site

    Příbram, 261 01, Czechia

  • Research Site

    Avellino, 83100, Italy

  • Research Site

    Bari, 70124, Italy

  • Research Site

    Benevento, 82100, Italy

  • Research Site

    Catania, 95126, Italy

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    Genova, 16128, Italy

  • Research Site

    Pisa, 56100, Italy

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    Roma, 00100, Italy

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    Roma, 00144, Italy

  • Research Site

    Roma, 00161, Italy

  • Research Site

    Treviglio, 24047, Italy

  • Research Site

    Fukuoka, 811-1395, Japan

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    Hamamatsu, 430-0906, Japan

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    Kagoshima, 892-0833, Japan

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    Kumamoto, 860-8556, Japan

  • Research Site

    Matsuyama, 791-0280, Japan

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    Mitaka-shi, 181-8611, Japan

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    Nishinomiya-shi, 663-8501, Japan

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    Osaka, 540-0006, Japan

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    Sakaishi, 590-0064, Japan

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    Suita-shi, 565-0871, Japan

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    Mexico City, 6760, Mexico

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    Mérida, 97000, Mexico

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    Monterrey, 64000, Mexico

  • Research Site

    Monterrey, 64060, Mexico

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    Monterrey, 64710, Mexico

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    Lima, Lima 18, Peru

  • Research Site

    Lima, LIMA 27, Peru

  • Research Site

    Lima, LIMA 33, Peru

  • Research Site

    Lima, LIMA 41, Peru

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    Katowice, 40-635, Poland

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    Lodz, 90-242, Poland

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    Lublin, 20-718, Poland

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    Brăila, 810325, Romania

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    Craiova, 200347, Romania

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    Onești, 601048, Romania

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    Timișoara, 300239, Romania

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    Barnaul, 656052, Russia

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    Moscow, 115478, Russia

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    Omsk, 644013, Russia

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    Ryazan, 390046, Russia

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    Saint Petersburg, 191014, Russia

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    Saint Petersburg, 195271, Russia

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    Saint Petersburg, 197022, Russia

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    Saint Petersburg, 197758, Russia

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    Tomsk, 634028, Russia

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    Bardejov, 085 01, Slovakia

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    Bratislava, 814 65, Slovakia

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    Bratislava, 833 10, Slovakia

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    Trenčín, 91171, Slovakia

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    Cape Town, 7570, South Africa

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    Cape Town, 7700, South Africa

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    Cape Town, 7925, South Africa

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    Pietermaritzburg, 3201, South Africa

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    Pretoria, 0001, South Africa

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    Pretoria, 0081, South Africa

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    Madrid, 28034, Spain

  • Research Site

    Madrid, 28050, Spain

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    Pamplona, 31008, Spain

  • Research Site

    Pozuelo de Alarcón, 28223, Spain

  • Research Site

    Sabadell, 8208, Spain

  • Research Site

    Seville, 41009, Spain

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    Seville, 41013, Spain

  • Research Site

    Seville, 41014, Spain

  • Research Site

    Valencia, 46014, Spain

  • Research Site

    Valencia, 46026, Spain

  • Research Site

    Taichung, 40447, Taiwan

  • Research Site

    Taipei, 10449, Taiwan

  • Research Site

    Taipei, 112, Taiwan

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    Taipei, 235, Taiwan

  • Research Site

    Ankara, 06100, Turkey (Türkiye)

  • Research Site

    Gaziantep, 27310, Turkey (Türkiye)

  • Research Site

    Cherkasy, 18009, Ukraine

  • Research Site

    Dnipro, 49102, Ukraine

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    Donetsk, 83092, Ukraine

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    Ivano-Frankivsk, 76014, Ukraine

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    Kharkiv Region, 61070, Ukraine

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    Kyiv, 3115, Ukraine

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    Lviv, 79031, Ukraine

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    Mariupol, 87500, Ukraine

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    Uzhhorod, 88000, Ukraine

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    Vinnytsia, 21029, Ukraine

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    Airdrie, ML6 0JS, United Kingdom

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    Derby, DE22 3NE, United Kingdom

  • Research Site

    Stoke-on-Trent, ST4 6QG, United Kingdom

Conditions

Explore the condition pages connected to this study.

HORMONE RECEPTOR-POSITIVE BREAST CANCER