New hope for advanced breast cancer: early trial tests experimental drug combinations

NCT ID NCT03332797

Summary

This early-stage trial is testing the safety and appropriate dosing of an experimental drug called GDC-9545 for advanced breast cancer. The study involves 181 patients with estrogen receptor-positive breast cancer that has spread or returned. Researchers are testing GDC-9545 alone and in combination with other cancer drugs to understand side effects and see if it shows early signs of helping control the cancer.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Barts Health NHS Trust

    London, E1 2ES, United Kingdom

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Centro Oncologioco MD Anderson Internacional

    Madrid, 28033, Spain

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital General Universitario Gregorio Maranon

    Madrid, 28007, Spain

  • Hospital Quiron Barcelona

    Barcelona, 08023, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • ICO L'Hospitalet

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • Massachusetts General Hospital.

    Boston, Massachusetts, 02115, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center

    Gyeonggi-do, 410-769, South Korea

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • St Vincent's Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • The Royal Marsden Hospital

    Suttton, SM2 5PT, United Kingdom

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37204, United States

Conditions

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