New hope for hard-to-treat breast cancer: triple-drug combo enters human trials

NCT ID NCT07330544

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests whether adding two targeted drugs (entinostat and anlotinib) to the standard hormone therapy fulvestrant can shrink tumors or slow cancer growth in people with a common type of advanced breast cancer (HR+/HER2-). About 118 adults whose cancer returned or worsened after prior treatments will receive the drug combinations. The goal is to see if the new combinations work better than current options, while monitoring side effects closely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhejiang Cancer Hospital

    RECRUITING

    Zhejiang, Hangzhou, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.